![Anti-Mouse AGO2 Antibody [A1279] - ABMIUM](http://www.abmium.com/cdn/shop/files/FVc8Oycu.jpg?v=1781563580&width=520)
ElabscienceABMIUM Verified™
Anti-Maus AGO2 Antikörper [A1279]
SKU: ABM875-1Primäre Antikörper
- Target
- AGO2
- Reactivity
- Maus
- Applications
- IHC-P, IP
- Host
- Kaninchen
From£89.60£112.00
Save 20%
Available to orderABMIUM target intelligence
argonaute RISC catalytic component 2
AGO2 (argonaute RISC catalytic component 2; protein argonaute-2) is the catalytic Argonaute protein of RNA-induced silencing complexes. Loaded with miRNAs or siRNAs, AGO2 guides sequence-specific gene silencing and can cleave highly complementary target RNAs.
Read full target overview
![Anti-Human/Mouse/Rat AGO2 Antibody [B542] - ABMIUM](http://www.abmium.com/cdn/shop/files/oFndH0AX.jpg?v=1781564381&width=520)
Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Protein argonaute-2 binds short guide RNAs within the RNA-induced silencing complex (RISC). Guide miRNAs or siRNAs direct AGO2 to complementary mRNAs; highly complementary targets can undergo AGO2-mediated endonucleolytic cleavage, while partially complementary targets can be repressed at the level of translation.
AGO2 is central to studies of RNA interference, miRNA function, RISC assembly, small-RNA loading and sequence-specific RNA cleavage. Researchers commonly examine AGO2 abundance, localization, RNA loading and target engagement when dissecting post-transcriptional gene regulation.
Names used across publications, databases and supplier catalogues.