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Immunoprecipitation Protocol: IP, Co-IP and Protein Enrichment
Immunoprecipitation (IP) is a widely used biochemical technique for the selective isolation and removal of enrichment of a target protein from complex biological samples using antigen-antibody interactions. The method enables downstream applications such as Western blotting, mass spectrometry, and functional assays. Variants of IP, including co-immunoprecipitation (co-IP), are particularly valuable for studying protein-protein interactions under native or near-physiological conditions.
