ABM-16780
CollaboratorElabscience
Target
ALK-1/ACVRL1Purity
>97% by SDS-PAGEMol. weight
37.4 kDaActivity
1. Measured by its ability to bind Human ENG-Fc, latent T...Species
Human
1. Measured by its ability to bind Human ENG-Fclatent TGFB1-Hismouse ENG-His in functional Elisa. 2. Measured by its ability to inhibit BMP9 induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. DavidL. et al. (2007) Blood 109:1953. The ED50 for this effect is typically 5-15 ng/mL in the presence of 2 ng/mL of recombiant human BMP9.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.