ABM-16107
CollaboratorElabscience
Target
RANKL/TNFSF11Purity
>85% by SDS-PAGEMol. weight
20.5 kDaActivity
1. Immobilized human TNFSF11 at 2 μg/ml (100 μl/well) can...Species
Human
1. Immobilized human TNFSF11 at 2 μg/ml (100 μl/well) can bind biotinylated human Osteoprotegerin hFcThe EC50 of human Osteoprotegerin hFc is 5-40 ng/ml.
2. The bioactivity of hRANKL was determined by measuring the ability of hRANKL to induce TRAP activity in Raw 264. 7 cells. The ED50 for this effect is typically 1.5-7.5 ng/mL.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.