ABM-16622
CollaboratorElabscience
Target
Osteoprotegerin/TNFRSF11BPurity
>97% by SDS-PAGEMol. weight
45.3 kDaActivity
1. Measured by its ability to inhibit TRAIL-mediated cyto...Species
Human
1. Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is typically 5-20 ng/mL in the presence of 20 ng/mL Recombinant Human TRAIL/TNFSF10.2. Immobilized human TNFRSF11B-His at 10 μg/ml (100 μl/well) can bind human Fc-TNFSF11 with a linear ranger of 3. 125-200 ng/mL.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.