ABM-16711
CollaboratorElabscience
Target
IL2Ra/CD25Purity
>97% by SDS-PAGEMol. weight
23.3 kDaActivity
1. Using the Octet RED System, the affinity constant (Kd)...Species
Human
1. Using the Octet RED Systemthe affinity constant (Kd) of Human IL2RA-his bound to Human IL2 was 35nM. 2. Measured by its ability to inhibit IL2-dependent proliferation of MO7e human megakaryocytic leukemic cells in the presence of 30 ng/mL of recombinant human IL-2. The ED50 for this effect is 0.15-0.75μg/mL.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.