STAT3 Mouse mAb from ELK Biotechnology
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STAT3 Mouse mAb is a research-use antibody from ELK Biotechnology for studying STAT3 in WB, IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
Signal transducer and activator of transcription 3, also known as STAT3, is a transcription factor which in humans is encoded by the STAT3 gene. Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities.
| Validation evidence captions | Western blot analysis of 1) Hela, 2)3T3, 3) PC12 with STAT3 Mouse mAb EM1207 diluted at 1:2,000. | Immunohistochemical analysis of paraffin-embedded Human Colon Caricnoma using STAT3（EM1207）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Mouse Brain Tissue using STAT3（EM1207）Mouse mAb diluted at 1:200. |
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Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
STAT3 identifies signal transducer and activator of transcription 3 in Homo sapiens (Human). This target record connects NCBI Gene 6774, UniProtKB P40763 and related ABMIUM catalogue products.
Biological function: STAT3 is a signal transducer and transcription factor activated downstream of multiple cytokine and growth-factor receptors. Following phosphorylation and dimerisation, STAT3 can translocate to the nucleus and regulate gene expression controlling processes including proliferation, survival, differentiation and immune responses.
