Manufactured by:Elabscience
Save 20%ABMIUM Verified™RUO

Recombinant Human BRCA1 Protein (His Tag)

Recombinant Human BRCA1 Protein (His Tag) supplied by Elabscience with collaborator-provided technical specifications.

SKU:
ABM14023-1
Product type
Recombinant Proteins
TargetBRCA1
Species / reactivityHuman
Purity>95% by SDS-PAGE

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Recombinant Human BRCA1 Protein (His Tag) is a research-use recombinant protein from Elabscience preparation representing BRCA1 supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling, Cell Biology, Cancer
Also known as
BRCA 1, BRCA1, BRCA1 DNA repair associated, BRCA1/BRCA2 containing complex subunit 1, BRCA1/BRCA2-containing complex, BRCAI, BRCC 1, BRCC1, Breast Cancer 1, Breast Cancer 1 Early Onset, Breast and ovarian cancer susceptibility protein 1, Breast cance, subunit 1
Modification
N-His
Molecular weight
28.8 kDa
Form / buffer
Lyophilized
Endotoxin level
< 10 EU/mg of the protein as determined by the LAL method
Sequence
Ser1610-Tyr1863
Technical note
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesBioactivityBindingCell-BasedIn VivoELISA Capture
Human
Identifiers & database references
Supplier SKU / catalogue number
PDEH100689_100ug
Gene symbol
BRCA1
Gene ID
672
UniProt accession
P38398-1
Storage, stability & shipping
Shelf life
12 months
Shipped at
This product is provided as lyophilized powder which is shipped with ice packs.
Short-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Long-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Aliquoting guidance
Reconstitute entire vial immediately. Aliquot working stock; avoid repeated freeze-thaw.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

BRCA1BRCA1 DNA repair associated

View target guide

BRCA1 (BRCA1 DNA repair associated; breast cancer type 1 susceptibility protein) is a nuclear genome-maintenance protein and E3 ubiquitin ligase central to DNA-damage responses, double-strand-break repair and genomic stability.

Biological function: BRCA1 forms a functional heterodimer with BARD1 that has E3 ubiquitin-protein ligase activity. The complex participates in cellular responses to DNA damage and helps coordinate DNA double-strand-break repair, homologous recombination, ubiquitin signalling and maintenance of genome integrity.

Organism
Homo sapiens (Human)
NCBI Gene
672
UniProtKB
P38398
Elabscience
£364.00£291.20