CNTF rabbit pAb from ELK Biotechnology
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CNTF rabbit pAb is a research-use antibody from ELK Biotechnology for studying CNTF in WB workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010],
| Specificity | CNTF protein(A218) detects endogenous levels of CNTF |
|---|---|
| Validation evidence captions | Western blot analysis of 1) Hela, 2)Mouse Brain Tissue, 3)Rat Brain Tissue with CNTF Rabbit pAb diluted at 1:2,000. |
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CNTF identifies ciliary neurotrophic factor in Homo sapiens (Human). This target record connects NCBI Gene 1270, UniProtKB P26441 and related ABMIUM catalogue products.
Biological function: Ciliary neurotrophic factor (CNTF) is a neurotrophic cytokine that supports the survival and differentiation of multiple neuronal populations and signals through a receptor complex containing CNTFR, LIFR and IL6ST/gp130.
