Manufactured by:ELK Biotechnology
RUO

AK1 rabbit pAb

AK1 rabbit pAb from ELK Biotechnology

SKU:
ABM108445
Product type
Primary Antibody
TargetAK1
ApplicationsIHC, IF, ELISA
Species / reactivityHuman, Mouse, Rat
Expression systemChondrosarcoma Lung Metastasis,Colon,Fetal brain cortex,Retina,Skeletal muscle,Synovial mem
PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

AK1 rabbit pAb is a research-use antibody from ELK Biotechnology for studying AK1 in IHC, IF, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

adenylate kinase 1(AK1) Homo sapiens This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],

Additional antibody information

Specificity AK1 Polyclonal Antibody detects endogenous levels of AK1 protein.
Validation evidence captions Immunofluorescence analysis of HepG2 cells, using KAD1 Antibody . The picture on the right is blocked with the synthesized peptide. | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using KAD1 Antibody . The picture on the right is blocked with the synthesized peptide.
Key facts & specifications
Research areas
>>Purine metabolism, >>Thiamine metabolism, >>Metabolic pathways, >>Nucleotide metabolism, >>Biosynthesis of cofactors
Also known as
AK1; Adenylate kinase isoenzyme 1; AK 1; ATP-AMP transphosphorylase 1; Myokinase
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human KAD1 . AA range:101-150
Cellular localization
Cytoplasm.
Assay type
Antibody validation/application
Source organism
Rabbit
Molecular weight
22kD
Concentration
1 mg/ml
Working concentration
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Sequence fragment
AA range: 101-150
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Mouse
Rat
Identifiers & database references
Supplier SKU / catalogue number
ES5120
UniProt entry
P00568
Storage, stability & shipping
Storage conditions
'-20°C/1 year
Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ELK Biotechnology
£220.00