HURP rabbit pAb from ELK Biotechnology
Know who made it. See the evidence. Buy through one marketplace.
HURP rabbit pAb is a research-use antibody from ELK Biotechnology for studying HURP in WB, ELISA workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
developmental stage:Elevated levels of expression detected in the G2/M phase of synchronized cultures of HeLa cells.,function:Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells.,PTM:Ubiquitinated, leading to its degradation.,similarity:Belongs to the SAPAP family.,subcellular location:Localizes to the spindle poles in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.,subunit:Interacts with CDC2. Interacts with the C-terminal proline-rich region of FBXO7. Recruited by FBXO7 to a SCF (SKP1-CUL1-F-box) protein complex in a CDC2/Cyclin B-phosphorylation dependent manner. Interacts with CDH1.,tissue specificity:Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta.,
| Specificity | HURP Polyclonal Antibody detects endogenous levels of HURP protein. |
|---|---|
| Validation evidence captions | Western Blot analysis of various cells using HURP Polyclonal Antibody | Western Blot analysis of A549 cells using HURP Polyclonal Antibody | Western blot analysis of lysates from A549, 293, and HUVEC cells, using DLGAP5 Antibody. The lane on the right is blocked with the synthesized peptide. | Western blot analysis of the lysates from HT-29 cells using DLGAP5 antibody. |
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
