Manufactured by:ELK Biotechnology
RUO

IkB α Rabbit pAb

IkB α Rabbit pAb from ELK Biotechnology

SKU:
ABM102203
Product type
Primary Antibody
TargetIkB α
ApplicationsWB, IHC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

IkB α Rabbit pAb is a research-use antibody from ELK Biotechnology for studying IkB α in WB, IHC workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.

Additional antibody information

Validation evidence captions Immunohistochemical analysis of paraffin-embedded Rat Kidney Tissue using IkBα(EA339)Rabbit pAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Stomach Tissue using IkBα(EA339)Rabbit pAb diluted at 1:200. | Western blot analysis of 1) Hela Cell Lysate, 2)PC12 Cell Lysate, 3) 3T3 Cell Lysate using IkB α (EA339)Rabbit pAb diluted at 1:1000.
Key facts & specifications
Research areas
Antibody Research
Also known as
I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB 1:500-1,000 IHC 1:100-200
Immunogen
Recombinant Protein
Observed band
40kDa
Cellular localization
Cytoplasm, Nucleus
Assay type
Antibody validation/application
Source organism
Rabbit
Concentration
1mg/mL
Working concentration
WB 1:500-1,000 IHC 1:100-200
Form / buffer
Liquid
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Mouse
Rat
Identifiers & database references
Supplier SKU / catalogue number
EA339
UniProt entry
P25963
Storage, stability & shipping
Storage conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Long-term storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Storage warning
Avoid repeated freeze-thaw cycles.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ELK Biotechnology
£220.00