Akt1 Rabbit pAb from ELK Biotechnology
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Akt1 Rabbit pAb is a research-use antibody from ELK Biotechnology for studying Akt1 in WB, IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription and cell migration. Akt1 is involved in cellular survival pathways, by inhibiting apoptotic processes. Akt1 is also able to induce protein synthesis pathways, and is therefore a key signaling protein in the cellular pathways that lead to skeletal muscle hypertrophy, and general tissue growth.
| Validation evidence captions | Western blot analysis of 1) Hela, 2)3T3, 3) PC12 with Akt1 Rabbit pAb EA243 diluted at 1:2,000. | Immunohistochemical analysis of paraffin-embedded Human Breast Caricnoma using Akt1（EA243）Rabbit pAb diluted at 1:200. |
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Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
AKT serine/threonine kinase 1 (AKT1), also known as protein kinase B alpha (PKB alpha), is a PI3K-regulated signalling kinase. This ABMIUM record links human AKT1 (NCBI Gene 207; UniProt P31749) to catalogue-backed research products.
Biological function: AKT1 is a serine/threonine kinase activated downstream of phosphoinositide 3-kinase signalling. It integrates growth-factor and receptor signals that regulate cell survival, proliferation, metabolism and angiogenic responses.
