Smad2 Rabbit pAb from ELK Biotechnology
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Smad2 Rabbit pAb is a research-use antibody from ELK Biotechnology for studying Smad2 in WB, IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
SMAD2 is a protein that in humans is encoded by the SMAD2 gene. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD2 mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein.
| Validation evidence captions | Western blot analysis of 1) Hela, 2)Jurkat, 3) C2C12, 4) PC12 with Smad2 Rabbit pAb EA241 diluted at 1:2,000. | Immunohistochemical analysis of paraffin-embedded Mouse Heart Tissue using Smad2 (EA241）Rabbit pAb diluted at 1:200. |
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Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
SMAD2 identifies SMAD family member 2 in Homo sapiens (Human). This target record connects NCBI Gene 4087, UniProtKB Q15796 and related ABMIUM catalogue products.
Biological function: SMAD family member 2 (SMAD2; MADH2) is a receptor-regulated SMAD transcriptional mediator in transforming growth factor beta (TGF-beta) and activin signalling. Activated type I receptors phosphorylate SMAD2, enabling complexes with SMAD4 that regulate target-gene transcription.
