Manufactured by:Boster Bio
ABMIUM Verified™RUO

Human MCAM/CD146 ELISA Kit PicoKine®

ELISA Kit supplied by Boster Bio

SKU:
ABM33327
Product type
ELISA Kits
TargetCell surface glycoprotein MUC18
ApplicationsELISA
Species / reactivityHuman
Sample typecell culture supernatants and serum.
PurityNatural and recombinant human MCAM

Manufacturer provenance

Manufactured by:
Boster Bio
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Human MCAM/CD146 ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Cell surface glycoprotein MUC18 in cell culture supernatants and serum. samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.

Human MCAM/CD146 ELISA Kit PicoKine® (96 Tests). Quantitate Human MCAM in cell culture supernatants and serum. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

CD146 (cluster of differentiation 146) also known as the melanoma cell adhesion molecule (MCAM) or cell surface glycoprotein MUC18, is a 113kDa cell adhesion molecule currently used as a marker for endothelial cell lineage. In humans, the CD146 protein is encoded by the MCAM gene. By radiation hybrid analysis, it mapped the CD146 gene to chromosome 11q23.3.It is a member of the immunoglobulin superfamily, is homologous to several cell adhesion molecules and is associated with tumor progression and the development of metastasis in human malignant melanoma. CD146 has been demonstrated to appear on a small subset of T and B lymphocytes in the peripheral blood of healthy individuals. The CD146+ T cells display an immunophenotype consistent with effector memory cells and have a distinct gene profile from the CD146- T cells.CD146 has been seen as a marker for mesenchymal stem cells isolated from multiple adult and fetal organs, and its expression may be linked to multipotency; mesenchymal stem cells with greater differentiation potential express higher levels of CD146 on the cell surface.

Product information

How to evaluate Human MCAM/CD146 ELISA Kit PicoKine®

Assess this research-use product against the requirements of your experimental workflow before ordering.

  • Confirm the supported sample matrices, assay principle and measurement range.
  • Review sensitivity, precision, standard-curve and control requirements in the supplied protocol.
  • Check storage conditions, preparation steps and required laboratory equipment before starting.

If a specification or current document is not shown, contact ABMIUM scientific support for assistance before use.

Key facts & specifications
Also known as
CD146; MCAM; MUC18
Cross-reactivity
There is no detectable cross-reactivity with other relevant proteins.
Immunogen
Expression system for standard: NS0; Immunogen sequence: V24-G559
Sensitivity
<10 pg/ml
Detection range
62.5 pg/ml - 4,000 pg/ml
Sequence fragment
Expression system for standard: NS0; Immunogen sequence: V24-G559
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Sample type validation

Sample compatibility evidence using the same validation key.

Sample typeSample CompatibilityAssay RangeSensitivitySpecificity
cell culture supernatants and serum.
Identifiers & database references
Supplier SKU / catalogue number
EK1675
Gene symbol
MCAM
Gene ID
4162
UniProt accession
P43121
Storage, stability & shipping
Shelf life
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Storage conditions
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Shipped at
Ambient or cold-chain dependent on product format
Short-term storage
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Long-term storage
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Compliance & documents
CE marked
No
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Boster Bio
£442.00