Manufactured by:ELK Biotechnology
RUO

Tubulin α rabbit pAb

Tubulin α rabbit pAb from ELK Biotechnology

SKU:
ABM109729
Product type
Primary Antibody
TargetTubulin α
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse, Rat
Expression systemExpressed at a high level in fetal brain.
PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Tubulin α rabbit pAb is a research-use antibody from ELK Biotechnology for studying Tubulin α in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

Additional antibody information

Specificity The antibody detects endogenous Tubulin α
Validation evidence captions Western blot analysis of HELA 293T Cell Lysate using antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Key facts & specifications
Research areas
>>Phagosome, >>Apoptosis, >>Tight junction, >>Gap junction, >>Alzheimer disease, >>Parkinson disease, >>Amyotrophic lateral sclerosis, >>Huntington disease, >>Prion disease, >>Pathways of neurodegeneration - multiple diseases, >>Pathogenic Escherichia coli infection, >>Salmonella infection
Also known as
Alpha-tubulin 1 antibody ALS22 antibody B ALPHA 1 antibody bA408E5.3 antibody H2 ALPHA antibody Hum a tub1 antibody Hum a tub2 antibody LIS3 antibody MGC171407 antibody MGC55332 antibody TBA4A_HUMAN antibody Testis-specific alpha-tubulin antibody TUBA1 antibody TUBA1A antibody tuba1l antibody Tuba4a antibody Tubulin alpha 1 chain antibody Tubulin alpha antibody Tubulin alpha-1 chain antibody tubulin alpha-1B chain antibody Tubulin alpha-4A chain antibody Tubulin H2-alpha antibody Tubulin, alpha 1 (testis specific) antibody tubulin, alpha 1, like antibody Tubulin, alpha 4a antibody Tubulin, alpha, testis-specific antibody Tubulin, alpha-1 antibody
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB 1:500-2000, ELISA 1:10000-20000
Immunogen
Synthetic peptide from human protein at AA range: 380-420
Observed band
15kD
Cellular localization
Cytoplasm, cytoskeleton.
Assay type
Antibody validation/application
Source organism
Rabbit
Concentration
1 mg/ml
Working concentration
WB 1:500-2000, ELISA 1:10000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Sequence fragment
AA range: 380-420
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Mouse
Rat
Identifiers & database references
Supplier SKU / catalogue number
ES8586
UniProt entry
Q71U36/P68363/Q9BQE3/Q13748/P68366/Q9NY65
Storage, stability & shipping
Storage conditions
'-20°C/1 year
Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ELK Biotechnology
£220.00