CREB rabbit pAb

CREB rabbit pAb

CREB rabbit pAb
Manufactured by:ELK Biotechnology
RUO

CREB rabbit pAb

CREB rabbit pAb from ELK Biotechnology

SKU:
ABM106917
Product type
Primary Antibody
TargetCREB-1
ApplicationsWB
Species / reactivityHuman
Expression systemEye,Placenta,Spleen,Testis,
PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

CREB rabbit pAb is a research-use antibody from ELK Biotechnology for studying CREB-1 in WB workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

Additional antibody information

Specificity The antibody detects endogenous CREB protein.
Validation evidence captions Western blot analysis of Hela, Rabbit pAb diluted at 1:2000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Key facts & specifications
Research areas
>>cGMP-PKG signaling pathway, >>cAMP signaling pathway, >>PI3K-Akt signaling pathway, >>AMPK signaling pathway, >>Longevity regulating pathway, >>Adrenergic signaling in cardiomyocytes, >>Osteoclast differentiation, >>Antigen processing and presentation, >>TNF signaling pathway, >>Circadian rhythm, >>Circadian entrainment, >>Thermogenesis, >>Cholinergic synapse, >>Dopaminergic synapse, >>Insulin secretion, >>Estrogen signaling pathway, >>Melanogenesis, >>Thyroid hormone synthesis, >>Glucagon signaling pathway, >>Renin secretion, >>Aldosterone synthesis and secretion, >>Relaxin signaling pathway, >>Cortisol synthesis and secretion, >>Parathyroid hormone synthesis, secretion and action, >>Insulin resistance, >>Cushing syndrome, >>Growth hormone synthesis, >>Vasopressin-regulated water reabsorption, >>Huntington disease, >>Prion disease, >>Cocaine addiction, >>Amphetamine addiction, >>Alcoholism, >>Tuberculosis, >>Hepatitis B, >>Human cytomegalovirus infection, >>Human papillomavirus infection, >>Human
Also known as
CREB1; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1:1000-2000
Immunogen
Recombinant Protein of Cyclic AMP-responsive element-binding protein 1
Observed band
37,43kD
Cellular localization
Nucleus .
Assay type
Antibody validation/application
Source organism
Rabbit
Working concentration
WB: 1:1000-2000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Form / buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Identifiers & database references
Supplier SKU / catalogue number
ES20777
UniProt entry
P16220
Storage, stability & shipping
Storage conditions
'-20°C/1 year
Long-term storage
'-20°C/1 year
Storage buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ELK Biotechnology
£220.00