Manufactured by:ELK Biotechnology
RUO

Cleaved-MPO 89k (A49) rabbit pAb

Cleaved-MPO 89k (A49) rabbit pAb from ELK Biotechnology

SKU:
ABM102875
Product type
Primary Antibody
TargetMPO
ApplicationsWB, ELISA
Species / reactivityHuman, Rat, Mouse
Expression systemLeukemia,Leukocyte,Liver,Plasma,Saliva,
PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Cleaved-MPO 89k (A49) rabbit pAb is a research-use antibody from ELK Biotechnology for studying MPO in WB, ELISA workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014],

Additional antibody information

Specificity Cleaved-MPO 89k (A49) Polyclonal Antibody detects endogenous levels of fragment of activated MPO 89k protein resulting from cleavage adjacent to A49.
Validation evidence captions Western Blot analysis of various cells using Cleaved-MPO 89k (A49) Polyclonal Antibody
Key facts & specifications
Research areas
>>Drug metabolism - other enzymes, >>Phagosome, >>Neutrophil extracellular trap formation, >>Transcriptional misregulation in cancer, >>Acute myeloid leukemia
Also known as
MPO; Myeloperoxidase; MPO
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from Cleaved-MPO 89k (A49) . at AA range: 40-120
Observed band
89kD
Cellular localization
Lysosome.
Assay type
Antibody validation/application
Source organism
Rabbit
Concentration
1 mg/ml
Working concentration
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Sequence fragment
AA range: 40-120
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Rat
Mouse
Identifiers & database references
Supplier SKU / catalogue number
ES1070
UniProt entry
P05164
Storage, stability & shipping
Storage conditions
'-20°C/1 year
Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MPOmyeloperoxidase

View target guide

MPO identifies myeloperoxidase in Homo sapiens (Human). This target record connects NCBI Gene 4353, UniProtKB P05164 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4353
UniProtKB
P05164
ELK Biotechnology
£220.00