Rat Neuropilin-2 ELISA Kit PicoKine®

Rat Neuropilin-2 ELISA Kit PicoKine® (96 Tests). Quantitate Rat Nrp2 in cell culture supernatants and cell lysates. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

NRP2 (Neuropilin-2), also called Npn2 or VEGF165R2, encodes a member of the neuropilin family of receptor proteins. The soluble NRP2 was secreted as a 62.5-kD protein following transfection in Chinese hamster ovary cells. The NRP2 gene is mapped to 2q33.3. The NRP2 gene contains 17 exons and spans about 112 kb. This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Mice with null mutations in genes encoding Sema3F, and its holoreceptor components Npn2 and plexin A3 (PLEXA3), exhibit increased dentate gyrus granule cell and cortical layer V pyramidal neuron spine number and size, and also aberrant spine distribution. Moreover, Sema3F promotes loss of spines and excitatory synapses in dissociated neurons in vitro, and in NRP2-null brain slices cortical layer V and dentate gyrus granule cells exhibit increased miniature excitatory postsynaptic current frequency. These disparate effects of secreted semaphorins are reflected in the restricted dendritic localization of NRP2 to apical dendrites and of Npn1 to all dendrites of cortical pyramidal neurons.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1345
Product category	PicoKine® ELISA Kits
Reactive species	Rat
Tested applications	ELISA
Gene name	NRP2
Protein name	Neuropilin-2
Sample type	cell culture supernatants and cell lysates.
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant rat Neuropilin-2
Immunogen	Expression system for standard: NS0; Immunogen sequence: Q23-D857
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	O35276
NCBI Gene ID	81527

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.