Mouse MIP-1Alpha/CCL3 ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›

Product Description
Chemokine (C-C motif) ligand 3 (CCL3), so known as Macrophage inflammatory protein-1alpha (MIP-1 alpha), is a protein that in humans is encoded by the CCL3 gene. It is a cytokine which belongs to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes. This gene is mapped to 17q12. CCL3 plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. It has been found that the activation of CCR5 by CCL3 ly and independently activates a G-protein signaling pathway through GNAI2 and a tyrosine phosphorylation signaling pathway through JAK2.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK0449 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Mouse |
| Tested applications | ELISA |
| Gene name | CCL3 |
| Protein name | C-C motif chemokine 3 |
| Sample type | cell culture supernatants, serum and plasma (heparin, EDTA, citrate). |
| Assay range | 7.8 pg/ml - 500 pg/ml |
| Sensitivity | <10 pg/ml |
| Specificity | Natural and recombinant mouse CCL3 |
| Immunogen | Expression system for standard: E.coli; Immunogen sequence: A24-A92 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P10855 |
| NCBI Gene ID | 20302 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | C-C motif chemokine 3 |
| Also known as | C C motif chemokine 3; CCL3; chemokine (C C motif) ligand 3; G0S19 1; LD78 alpha(4 69); LD78ALPHA; MIP 1 alpha; MIP1A; PAT 464.1; SCYA3; SIS beta; Small inducible cytokine A3 |
| Species reactivity | Mouse |
| Purity | Natural and recombinant mouse CCL3 |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <10 pg/ml |
| Detection range | 7.8 pg/ml - 500 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparinEDTAcitrate).
See sample validation ›
|
Sample Type Validation
4 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin | |||||
| EDTA | |||||
| citrate). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.