Human Uromodulin/umod ELISA Kit PicoKine®

Human Uromodulin/umod ELISA Kit PicoKine® (96 Tests). Quantitate Human UMOD in cell culture supernatants, serum and plasma (heparin). Sensitivity: 10pg/ml . The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

The Tamm–Horsfall glycoprotein (THP), also known as uromodulin, is a glycoprotein that in humans is encoded by the UMOD gene. The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1690
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	UMOD
Protein name	Uromodulin
Sample type	cell culture supernatants, serum and plasma (heparin).
Assay range	312 pg/ml - 20,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human Uromodulin
Immunogen	Expression system for standard: NS0; Immunogen sequence: D25-F587
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P07911
NCBI Gene ID	7369

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.