Human Syndecan-4/SDC4 ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›
Product Description
Syndecan-4 (SDC4) is a protein that in humans is encoded by the SDC4 gene. The protein is found as a homodimer and is a member of the syndecan proteoglycan family. It is mapped to 20q13.12. Syndecan-4 is one of the four vertebrate syndecans and has a molecular weight of ~20 kDa. It is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. Syndecan-4 also regulates the actin cytoskeleton, cell adhesion, and cell migration. In addition, Syndecan-4 can activate protein kinase C (PKC). The variable domain of syndecan-4 could be a site of self-association. What’s more, Syndecan-4 also binds to phosphatidylinositol (4,5)-bisphosphate (PIP2) through the variable domain and increases PKC activity ten-fold.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK1356 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | SDC4 |
| Protein name | Syndecan-4 |
| Sample type | cell culture supernatants, cell lysates and serum. |
| Assay range | 62.5 pg/ml - 4,000 pg/ml |
| Sensitivity | <10 pg/ml |
| Specificity | Natural and recombinant human Syndecan-4 |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: E19-E145 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P31431 |
| NCBI Gene ID | 6385 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Syndecan-4 |
| Also known as | Amphiglycan; Ryudocan core protein; SDC4; SYND4; syndecan 4 |
| Species reactivity | Human |
| Purity | Natural and recombinant human Syndecan-4 |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <10 pg/ml |
| Detection range | 62.5 pg/ml - 4,000 pg/ml |
| Sample types |
cell culture supernatantscell lysates and serum.
See sample validation ›
|
Sample Type Validation
2 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| cell lysates and serum. |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.