Human Serpin C1/Antithrombin-III PicoKine® Quick ELISA Kit

Human Serpin C1/Antithrombin-III PicoKine® Quick ELISA Kit (120 minutes, 96 Tests). Quantitate Human SERPINC1 in cell culture supernatants, serum, plasma (heparin, EDTA, citrate) and urine. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Antithrombin III is the most important inhibitor of thrombin and other coagulation proteinases. It belongs to the serine proteinase inhibitor (serpin) superfamily of inhibitors and structurally related proteins, which contain reactive centers that have evolved to attract and entrap certain proteinases. Inherited antithrombin III deficiency (AT3D) is a risk factor for the early development of venous thromboembolism (THPH7). Antithrombin III regulates clot formation both by inhibiting thrombin activity ly and by interfering with earlier stages of the clotting cascade. By in situ hybridization and quantitative analysis of DNA dosage in carriers of chromosome 1 deletions, AT3 is mapped to 1q23-q25. The AT3 gene has 7 exons. It contains 9 complete and 1 partial repetitive ALU sequence elements, which occur in the introns of the gene at a higher frequency (about 22% of the intron sequence) than in the genome as a whole (about 5%).

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	FEK1393
Product category	Quick ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	SERPINC1
Protein name	Antithrombin-III
Sample type	cell culture supernatants, serum, plasma (heparin, EDTA, citrate) and urine.
Assay range	312 pg/ml - 20,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human Serpin C1
Immunogen	Expression system for standard: NS0; Immunogen sequence: H33-K464
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P01008
NCBI Gene ID	462

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.