Human SEMA6D ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›

Product Description
Semaphorin 6D (Sema6D) is a 130 ? 135 kDa member of the Semaphorin family of axon guidance molecules. This gene is mapped to 15q21.1. Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK2060 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | SEMA6D |
| Protein name | Semaphorin-6D |
| Sample type | cell culture supernatants, serum and plasma (heparin, EDTA, citrate). |
| Assay range | 31.2 pg/ml - 2,000 pg/ml |
| Sensitivity | <20 pg/ml |
| Specificity | Natural and recombinant human SEMA6D |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: V21-N662 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | Q8NFY4 |
| NCBI Gene ID | 80031 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Semaphorin-6D |
| Also known as | Semaphorin-6D; SEMA6D; KIAA1479 |
| Species reactivity | Human |
| Purity | Natural and recombinant human SEMA6D |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <20 pg/ml |
| Detection range | 31.2 pg/ml - 2,000 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparinEDTAcitrate).
See sample validation ›
|
Sample Type Validation
4 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin | |||||
| EDTA | |||||
| citrate). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.