Human OPG (TNFRSF11B) / Osteoprotegerin ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›

Product Description
Osteoprotegerin (OPG) is identical to osteoclastogenesis inhibitory factor (OCIF), a soluble member of the tumor-necrosis factor receptor family that inhibits osteoclastogenesis. OPG is considered to play an important role in the regulation of bone resorption by modifying osteoclast differentiation. Osteoprotegerin is an independent risk factor for the progression of atherosclerosis and onset of cardiovascular disease. It can act as a soluble factor in the regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity. OPG system may play a critical role in the development of osteolytic bone disease in multiple myeloma and that targeting this system may have therapeutic potential. OPG also plays a role in the vascular system. The standard product used in this kit is recombinant OPG, a 55KDa glycoprotein.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK0480 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | TNFRSF11B |
| Protein name | Tumor necrosis factor receptor superfamily member 11B |
| Sample type | cell culture supernatants, serum, plasma (heparin, EDTA) , saliva and urine. |
| Assay range | 93.7 pg/ml - 6,000 pg/ml |
| Sensitivity | <5 pg/ml |
| Specificity | Natural and recombinant human OPG |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: E22-L401 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | O00300 |
| NCBI Gene ID | 4982 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Tumor necrosis factor receptor superfamily member 11B |
| Also known as | TNF receptor superfamily member 11b; OCIF; OPG; PDB5; TR1; TNFRSF11B |
| Species reactivity | Human |
| Purity | Natural and recombinant human OPG |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <5 pg/ml |
| Detection range | 93.7 pg/ml - 6,000 pg/ml |
| Sample types |
cell culture supernatantsserumplasma (heparinEDTA)saliva and urine.
See sample validation ›
|
Sample Type Validation
5 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum | |||||
| plasma (heparin | |||||
| EDTA) | |||||
| saliva and urine. |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.