Human MMP-7/Matrilysin ELISA Kit PicoKine®

Human MMP-7 ELISA Kit PicoKine® (96 Tests). Quantitate Human MMP7 in cell culture supernatants, serum, plasma (heparin) , saliva and urine. Sensitivity: 6pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Matrix metalloproteinase-7 (MMP-7) previously called putative metalloproteinase I (PUMP1) or matrilysin. The PUMP1 gene has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The PUMP I protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis. Matrilysin, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, matrilysin mRNA is regulated in a specific and distinct manner in normal and malignant tissues. Matrilysin has been shown to correlate with nodal or distant metastasis in colorectal carcinomas; however, its implication in early invasive colorectal carcinomas has not been determined.1 Matrilysin is also a mediator of pulmonary fibrosis and a potential therapeutic target. The standard product used in this kit is recombinant human MMP-7, consisting of 250 amino acids with the molecular mass of 28KDa. The detected MMP-7 includes zymogen and active enzyme.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK0463
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	MMP7
Protein name	Matrilysin
Sample type	cell culture supernatants, serum, plasma (heparin) , saliva and urine.
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<6 pg/ml
Specificity	Natural and recombinant human total MMP-7
Immunogen	Expression system for standard: NS0; Immunogen sequence: L18-K267
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P09237
NCBI Gene ID	4316

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.