Human MEP1A ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›
Product Description
Meprin A subunit alpha also known as endopeptidase-2 or PABA peptide hydrolase is the alpha subunit of the meprin A enzyme that in humans is encoded by the MEP1A gene. Meprin A subunit alpha, encoded by the **MEP1A** gene, is a component of the meprin A metalloproteinase complex, which is involved in extracellular matrix remodeling and proteolysis. Meprin A is a zinc-dependent endopeptidase found predominantly in the kidneys, intestines, and other tissues. It plays a crucial role in various physiological processes, including inflammation, tissue repair, and the processing of bioactive peptides. The alpha subunit, specifically, is a part of the hetero-oligomeric enzyme complex, which combines with the beta subunit to form an active enzyme. Abnormalities in meprin A function have been associated with several pathological conditions, including kidney diseases and cancer.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK1552 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | MEP1A |
| Protein name | Meprin A subunit alpha |
| Sample type | cell culture supernatants, serum and plasma (heparin, EDTA). |
| Assay range | 1.56 ng/ml - 100 ng/ml |
| Sensitivity | <50 pg/ml |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: V22-Q601 |
| Storage | Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | Q16819 |
| NCBI Gene ID | 4224 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Meprin A subunit alpha |
| Also known as | Endopeptidase 2; MEP1A; Meprin A subunit alpha; PABA peptide hydrolase; PPH alpha; PPHA |
| Species reactivity | Human |
| Shelf life | Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <50 pg/ml |
| Detection range | 1.56 ng/ml - 100 ng/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparinEDTA).
See sample validation ›
|
Sample Type Validation
3 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin | |||||
| EDTA). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.