Human Livin ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›
Product Description
BIRC7, also called KIAP or Livin, is a protein that in humans is encoded by the BIRC7 gene. This gene is mapped to 20q13.33. It encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. BIRC7 blocked apoptosis induced by BAX induction of cytochrome C release from mitochondria, and it also can block apoptosis induced by chemotherapeutic agents.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK1348 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | BIRC7 |
| Protein name | Baculoviral IAP repeat-containing protein 7 |
| Sample type | cell culture supernatants, serum and cell lysates. |
| Assay range | 156 pg/ml - 10,000 pg/ml |
| Sensitivity | <20 pg/ml |
| Specificity | Natural and recombinant human Livin |
| Immunogen | Expression system for standard: E.coli; Immunogen sequence: M1-S298 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | Q96CA5 |
| NCBI Gene ID | 79444 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Baculoviral IAP repeat-containing protein 7 |
| Also known as | BIRC7; KIAP; LIVIN; ML IAP; MLIAP; RING finger protein 50; RNF50 |
| Species reactivity | Human |
| Purity | Natural and recombinant human Livin |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <20 pg/ml |
| Detection range | 156 pg/ml - 10,000 pg/ml |
| Sample types |
cell culture supernatantsserum and cell lysates.
See sample validation ›
|
Sample Type Validation
2 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and cell lysates. |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.