Human Granzyme A ELISA Kit PicoKine®

Human Granzyme A ELISA Kit PicoKine® (96 Tests). Quantitate Human GZMA in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Granzyme A is a protein that in humans is encoded by the GZMA gene. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. GZMA induces caspase-independent apoptosis in a characteristic manner, except it causes a distinctive form of DNA damage: single-stranded DNA nicking. A target of GZMA is the SET complex, including HMGB2 and ANP32A.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1162
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	GZMA
Protein name	Granzyme A
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	15.6 pg/ml - 1,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human Granzyme A
Immunogen	Expression system for standard: NS0; Immunogen sequence: I29-V262
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P12544
NCBI Gene ID	3001

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.