Human GFRA2 ELISA Kit PicoKine®

Human GFRA2 ELISA Kit PicoKine® (96 Tests). Quantitate Human GFRA2 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

GDNF family receptor alpha-2 (GFRα2), also known as the neurturin receptor, is a protein that in humans is encoded by the GFRA2 gene. It is mapped to 8p21.3. The GFRA2 protein is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. They both bind the GFRA2 receptor. The receptor mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. GFRA2 (gene) has been shown to interact with GDNF.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK2072
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	GFRA2
Protein name	GDNF family receptor alpha-2
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA, citrate).
Assay range	312 pg/ml - 20,000 pg/ml
Sensitivity	<50 pg/ml
Specificity	Natural and recombinant human GFRA2
Immunogen	Expression system for standard: NS0; Immunogen sequence: S22-S444
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	O00451
NCBI Gene ID	2675

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.