Human Fractalkine/CX3CL1 ELISA Kit PicoKine®

Human Fractalkine/CX3CL1 ELISA Kit PicoKine® (96 Tests). Quantitate Human CX3CL1 in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk. Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice). CX3CL1 is produced as a long protein (with 373-amino acid in humans) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk permits it to bind to the surface of certain cells. However a soluble (90 kD) version of this chemokine has also been observed. Soluble CX3CL1 potently chemoattracts T cells and monocytes, while the cell-bound chemokine promotes strong adhesion of leukocytes to activated endothelial cells, where it is primarily expressed. CX3CL1 elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1. Its gene is located on human chromosome 16 along with some CC chemokines known as CCL17 and CCL22. It can act as a mediator of smooth muscle cell migration in human atherosclerosis, rather than mediate inflammatory cell recruitment.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK0356
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	CX3CL1
Protein name	Fractalkine
Sample type	cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<50 pg/ml
Specificity	Natural and recombinant human Fractalkine
Immunogen	Expression system for standard: NS0; Immunogen sequence: Q25-R339
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P78423
NCBI Gene ID	6376

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.