Human FASL / CD95LG / CD95 Ligand ELISA Kit PicoKine®

Human FASL / CD95LG / CD95 Ligand ELISA Kit PicoKine® (96 Tests). Quantitate Human FASLG in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 2pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Fas ligand (FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its binding with its receptor induces apoptosis. The human FASL gene consists of approximately 8 kb and is split into 4 exons. Fas ligand/receptor interactions play an important role in the regulation of the immune system and the progression of cancer. Fas ligand or FasL is a homotrimeric type II transmembrane protein. It signals through trimerization of FasR, which spans the membrane of the target cell. This trimerization usually leads to apoptosis, or cell death. Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external matrix metalloproteinase MMP-7.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK0337
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	FASLG
Protein name	Tumor necrosis factor ligand superfamily member 6
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA, citrate).
Assay range	15.6 pg/ml - 1,000 pg/ml
Sensitivity	<2 pg/ml
Specificity	Natural and recombinant human FASL
Immunogen	Expression system for standard: CHO; Immunogen sequence: P134-L281
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P48023
NCBI Gene ID	356

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.