Human DKK-3 PicoKine® Quick ELISA Kit
ELISA Kit supplied by Boster Bio Read more ›

Product Description
Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. It is mapped to 11p15.3. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Members of the Dkk-related family display unique patterns of mRNA expression in human and mouse tissues, and are secreted when expressed in 293T cells. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | FEK1323 |
| Product category | Quick ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | DKK3 |
| Protein name | Dickkopf-related protein 3 |
| Sample type | cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA) |
| Assay range | 156 pg/ml - 10,000 pg/ml |
| Sensitivity | <10 pg/ml |
| Specificity | Natural and recombinant Human DDK3 |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: A22-I350 |
| Storage | Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.) |
| UniProt | Q9UBP4 |
| NCBI Gene ID | 27122 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Dickkopf-related protein 3 |
| Also known as | Dickkopf 3; Dickkopf related protein 3; Dkk 3; DKK3; hDkk 3; REIC; RIG |
| Species reactivity | Human |
| Purity | Natural and recombinant Human DDK3 |
| Shelf life | Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.) |
| Sensitivity | <10 pg/ml |
| Detection range | 156 pg/ml - 10,000 pg/ml |
| Sample types |
cell culture supernatantscell lysatesserum and plasma (heparinEDTA)
See sample validation ›
|
Sample Type Validation
4 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| cell lysates | |||||
| serum and plasma (heparin | |||||
| EDTA) |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.