Human CYR61/CCN1 ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›
Product Description
Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. This gene is mapped to 1p22.3. CYR61 is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK1203 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | CYR61 |
| Protein name | CCN family member 1 |
| Sample type | cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk. |
| Assay range | 31.2 pg/ml - 2,000 pg/ml |
| Sensitivity | <10 pg/ml |
| Specificity | Natural and recombinant human CYR61 |
| Immunogen | Expression system for standard: CHO; Immunogen sequence: A22-D381 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | O00622 |
| NCBI Gene ID | 3491 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | CCN family member 1 |
| Also known as | CCN family member 1; CCN1; CYR61; cysteine-rich protein 61; GIG1; IBP 10; IGF binding protein 10; IGFBP 10; IGFBP10; Protein CYR61; Protein GIG1 |
| Species reactivity | Human |
| Purity | Natural and recombinant human CYR61 |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <10 pg/ml |
| Detection range | 31.2 pg/ml - 2,000 pg/ml |
| Sample types |
cell culture supernatantsserumplasma (heparinEDTA)salivaurine and human milk.
See sample validation ›
|
Sample Type Validation
6 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum | |||||
| plasma (heparin | |||||
| EDTA) | |||||
| saliva | |||||
| urine and human milk. |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.