Human CD125 ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›

Product Description
Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA also denotes its human gene. The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK2228 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | IL5RA |
| Protein name | Interleukin-5 receptor subunit alpha |
| Sample type | cell culture supernatants, serum and plasma (heparin, EDTA) |
| Assay range | 31.2 pg/ml - 2,000 pg/ml |
| Sensitivity | <15 pg/ml |
| Specificity | Natural and recombinant human IL5RA |
| Immunogen | Expression system for standard: CHO; Immunogen sequence: D21-E335 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | Q01344 |
| NCBI Gene ID | 3568 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Interleukin-5 receptor subunit alpha |
| Also known as | CD125; CDw125; HSIL5R3; IL 5 receptor subunit alpha; IL 5R alpha; IL 5R subunit alpha; IL 5RA; IL5R; IL5RA; IL-5RA; interleukin 5 receptor; alpha |
| Species reactivity | Human |
| Purity | Natural and recombinant human IL5RA |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <15 pg/ml |
| Detection range | 31.2 pg/ml - 2,000 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparinEDTA)
See sample validation ›
|
Sample Type Validation
3 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin | |||||
| EDTA) |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.