Human ADAM12 / MCMP ELISA Kit PicoKine®

Human ADAM12 / MCMP ELISA Kit PicoKine® (96 Tests). Quantitate Human ADAM12 in cell culture supernatants, serum, plasma (heparin) and urine. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

ADAM12 (Disintegrin and metalloproteinase domain-containing protein 12), also known as MLTN, is an enzyme that in humans is encoded by the ADAM12 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis. By RT-PCR and immunoblot analyses that expression of mouse Adam12 increases during muscle regeneration, while the levels of other ADAMs remain constant. Immunofluorescence analysis revealed staining of small, newly formed muscle fibers in regenerating but not normal adult muscle cells. By using of fluorescence in situ hybridization, the ADAM12 gene is mapped to human chromosome 10q26.3.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK0934
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	ADAM12
Protein name	Disintegrin and metalloproteinase domain-containing protein 12
Sample type	cell culture supernatants, serum, plasma (heparin) and urine.
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human ADAM12
Immunogen	Expression system for standard: CHO; Immunogen sequence: R29-S513
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	O43184
NCBI Gene ID	8038

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.