ABM99385
Dynein IC2 rabbit pAb
ISO 9001|ABMIUM Verified™|Antibody
Dynein IC2 rabbit pAb from ELK Biotechnology Read more ›
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Product Description
Dynein IC2 rabbit pAb is an ELK Biotechnology antibody for research workflows involving Dynein IC2.
Background
The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in this gene are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2010],
Additional antibody information
| Specificity | Dynein IC2 Polyclonal Antibody detects endogenous levels of Dynein IC2 protein. |
|---|---|
| Validation evidence captions | Western blot analysis of DNAI2 Antibody. The lane on the right is blocked with the DNAI2 peptide. | Western blot analysis of the lysates from RAW264.7cells using DNAI2 antibody. |
Key Facts
Product type
Primary Antibody›
Target: Dynein IC2
| Target | Dynein IC2 |
| Also known as | DNAI2; Dynein intermediate chain 2; axonemal; Axonemal dynein intermediate chain 2 |
| Concentration | 1 mg/ml |
| Working concentration | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Species reactivity | Human;Mouse;Rat;Chicken |
| Observed band | 70kD |
| Cellular localization | Cytoplasm, cytoskeleton, cilium axoneme . Dynein axonemal particle . Located in the proximal region of respiratory cilia. . |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Form / buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research area | >>Amyotrophic lateral sclerosis;>>Huntington disease;>>Pathways of neurodegeneration - multiple diseases |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Tested applications |
WBELISA |
| Dilution range | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DNAI2. AA range:71-120 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
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Citations
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Reactivity & Application Validation
4 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat | |||||||
| Chicken |
ABMIUM Validated™
WB
| Species | Dilution | Notes |
|---|---|---|
| Human | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. | — |
| Mouse | — | — |
| Rat | — | — |
| Chicken | — | — |
ABMIUM Validated™
ELISA
| Species | Dilution | Notes |
|---|
Specifications
Target
Dynein IC2
Also known as
DNAI2; Dynein intermediate chain 2; axonemal; Axonemal dynein intermediate chain 2
Concentration
1 mg/ml
Working concentration
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human;Mouse;Rat;Chicken
Tested applications
WBELISA
Immunogen
The antiserum was produced against synthesized peptide derived from human DNAI2. AA range:71-120
Observed band
70kD
Cellular localization
Cytoplasm, cytoskeleton, cilium axoneme . Dynein axonemal particle . Located in the proximal region of respiratory cilia. .
Dilution range
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage & Stability
Long-term storage
-20°C/1 year
Storage conditions
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & Certifications
ISO 9001
ISO 9001:2015 Certified
Manufactured under ISO 9001:2015 quality management standards.
RUO
For Research Use Only
Not intended for diagnostic or therapeutic use.
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