Phospho-ERK 1/2 (Y205/222) (7A6) Mouse mAb
Phospho-ERK 1/2 (Y205/222) (7A6) Mouse mAb from ELK Biotechnology Read more ›
Product Description
Phospho-ERK 1/2 (Y205/222) (7A6) Mouse mAb is an ELK Biotechnology antibody for research workflows involving Phospho-ERK 1/2 (Y205/222) (7A6).
Background
Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.
Additional antibody information
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-ERK1/2（EM1342）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Phospho-ERK1/2（EM1342）Mouse mAb diluted at 1:200. |
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Key Facts
| Target | Phospho-ERK 1/2 (Y205/222) (7A6) |
| Also known as | MAPK, Mitogen-activated protein Kinase, PRKM2,MK01 |
| Concentration | 1mg/mL |
| Working concentration | IHC 1:100-200 |
| Species reactivity | Human, Mouse, Rat |
| Observed band | 44,42kDa |
| Cellular localization | Nucleus |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
IHC |
| Dilution range | IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:100-200 | — |
| Mouse | — | — |
| Rat | — | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.