ABM92552
a-actinin (4A12) Mouse mAb
ISO 9001|ABMIUM Verified™|Antibody
a-actinin (4A12) Mouse mAb from ELK Biotechnology Read more ›
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Product Description
a-actinin (4A12) Mouse mAb is an ELK Biotechnology antibody for research workflows involving a-actinin (4A12).
Background
α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.
Additional antibody information
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Breast Carrcinoma Tissue using a-actinin（EM1261）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using a-actinin（EM1261）Mouse mAb diluted at 1:200. |
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Key Facts
Product type
Primary Antibody›
Target: a-actinin (4A12)
| Target | a-actinin (4A12) |
| Also known as | actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody |
| Concentration | 1mg/mL |
| Working concentration | IHC 1:100-200 |
| Species reactivity | Human, Rat, Mouse |
| Observed band | 103kDa |
| Cellular localization | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
IHC |
| Dilution range | IHC 1:100-200 |
| Immunogen | Recombinant Protein |
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Citations
ISO 9001
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Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
ABMIUM Validated™
IHC
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:100-200 | — |
| Rat | — | — |
| Mouse | — | — |
Specifications
Target
a-actinin (4A12)
Also known as
actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody
Concentration
1mg/mL
Working concentration
IHC 1:100-200
Form / buffer
Antibody solution
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Species reactivity
Human, Rat, Mouse
Tested applications
IHC
Immunogen
Recombinant Protein
Observed band
103kDa
Cellular localization
Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane
Dilution range
IHC 1:100-200
Storage & Stability
Avoid repeated freeze-thaw cycles.
Long-term storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Storage conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Compliance & Certifications
ISO 9001
ISO 9001:2015 Certified
Manufactured under ISO 9001:2015 quality management standards.
RUO
For Research Use Only
Not intended for diagnostic or therapeutic use.
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