Myosin Heavy Chain Mouse mAb
Myosin Heavy Chain Mouse mAb from ELK Biotechnology Read more ›
Product Description
Myosin Heavy Chain Mouse mAb is an ELK Biotechnology antibody for research workflows involving Myosin Heavy Chain.
Background
Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.
Additional antibody information
| Validation evidence captions | Immunofluorescence Staining of nematode tissue with MYH mouse mAb(11C2) diluted at 1:100. (Provide by Tsinghua University). | Immunofluorescence double Staining of fruit fly tissue with MYH mouse mAb(11C2)(Green) and F-actin mouse mAb(red) (Provide by NIBS). |
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Key Facts
| Target | Myosin Heavy Chain |
| Also known as | Bsh, CG17927, Dm II, Dmel\CG17927, DmMHC, DROMHC, DroMII, FBgn0002741, Ifm(2)2, l(2)36Ae, l(2)k10423, l(2)M66, Mhc, Mhc36B, mMHC, MRP, Myo, Myosin heavy chain, Nup, Sht, sMHC, Stp |
| Concentration | 1mg/mL |
| Working concentration | IHC 1:200 IF 1:100 |
| Species reactivity | Human, Mouse, Rat, Fruit Fly, Nematode |
| Observed band | 220kDa |
| Cellular localization | Cytoplasm, Thick filament |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
IHCIF |
| Dilution range | IHC 1:200 IF 1:100 |
| Immunogen | Synthetic Peptide |
Reactivity & Application Validation
5 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Mouse | |||||||
| Rat | |||||||
| Fruit Fly | |||||||
| Nematode |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:200 IF 1:100 | — |
| Mouse | — | — |
| Rat | — | — |
| Fruit Fly | — | — |
| Nematode | — | — |
| Species | Dilution | Notes |
|---|
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.