CD23 Mouse mAb
CD23 Mouse mAb from ELK Biotechnology Read more ›
Product Description
CD23 Mouse mAb is an ELK Biotechnology antibody for research workflows involving CD23.
Background
The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils.
Additional antibody information
| Validation evidence captions | IHC staining of Human tonsil tissue paraffin-embedded with CD23 mouse mAb（1E9）diluted at 1:200. |
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Key Facts
| Target | CD23 |
| Also known as | BLAST 2, CD23A, CLEC4J, Fc epsilon RII, FCE2, FCER2, IGEBF, Lymphocyte IgE receptor |
| Concentration | 1mg/mL |
| Working concentration | IHC 1:200 |
| Species reactivity | Human, Rat, Mouse |
| Observed band | 28,38,49kDa |
| Cellular localization | Cell membrane. Secreted |
| Form / buffer | Antibody solution |
| Research area | Antibody Research |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Tested applications |
IHC |
| Dilution range | IHC 1:200 |
| Immunogen | Synthetic Peptide |
Reactivity & Application Validation
3 speciess| Species | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Human | |||||||
| Rat | |||||||
| Mouse |
| Species | Dilution | Notes |
|---|---|---|
| Human | IHC 1:200 | — |
| Rat | — | — |
| Mouse | — | — |
Specifications
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.