Anti-RTF2 Antibody Picoband®
Primary Antibody supplied by Boster Bio Read more ›

Product Description
Replication termination factor 2 is a protein that in humans is encoded by the RTF2 gene. Replication Termination Factor 2, often abbreviated as RTF2, is a protein involved in the regulation and termination of DNA replication processes in eukaryotic cells. It plays a crucial role in ensuring the accurate completion of DNA synthesis during cell division by coordinating the termination of replication forks at specific sites along the DNA strands. RTF2 functions by interacting with other proteins and DNA sequences to facilitate the orderly disassembly of the replication machinery and the prevention of unnecessary re-replication of genomic regions. Its activity is tightly regulated to maintain genomic stability and fidelity, making it a key player in cell cycle control mechanisms. Studies on RTF2 have provided insights into the molecular mechanisms governing DNA replication termination and its implications for cellular function and genome maintenance.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | A16683-1 |
| Product category | Primary Antibodies |
| Reactive species | Human |
| Tested applications | ELISA, Flow Cytometry, IF/ICC, IHC, IHC-P, IP, WB |
| Available conjugations | Unconjugated, Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, Fluoro647 |
| Gene name | RTF2 |
| Protein name | Replication termination factor 2 |
| Immunogen | E.coli-derived human RTF2 recombinant protein (Position: D4-F306). Human RTF2 shares 87.8% and 88.1% amino acid (aa) sequence identity with mouse and rat RTF2, respectively. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Immunogen affinity purified. |
| Storage | At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing. |
| UniProt | Q9BY42 |
| NCBI Gene ID | 51507 |
Available variants
| Conjugation | Size |
|---|---|
| Unconjugated | 100 μg/vial |
| Biotin | 100 μg/vial |
| Cy3 | 100 μg/vial |
| Fluoro488 | 100 μg/vial |
| Fluoro550 | 100 μg/vial |
| Fluoro594 | 100 μg/vial |
| FITC | 100 μg/vial |
| HRP | 100 μg/vial |
| APC | 100 μg/vial |
| PE | 100 μg/vial |
| Fluoro647 | 100 μg/vial |
Key Facts
| Target | Replication termination factor 2 |
| Also known as | RTF2; C20orf43; RTFDC1; AD-007; CDA05; HSPC164; HSPC169; Replication termination factor 2; RTF2; Replication termination factor 2 domain-containing protein 1 |
| Concentration | Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
| Species reactivity | Human |
| Observed band | 37 kDa |
| Form / buffer | Lyophilized |
| Shelf life | At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing. |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated|Biotin|Cy3|Fluoro488|Fluoro550|Fluoro594|FITC|HRP|APC|PE|Fluoro647 |
| Tested applications |
ELISAFlow CytometryIF/ICCIHCIHC-PIPWB |
| Dilution range | Western blot, 0.25-0.5 μg/ml, Human Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human Immunoprecipitation, 0.5-2 μg/ml, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/ml, - |
| Immunogen | E.coli-derived human RTF2 recombinant protein (Position: D4-F306). Human RTF2 shares 87.8% and 88.1% amino acid (aa) sequence identity with mouse and rat RTF2, respectively. |
| Purification | Immunogen affinity purified. |
Reactivity & Application Validation
1 species| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | FLOW CYTOMETRY | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
Specifications
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Immunoprecipitation, 0.5-2 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/ml, -
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.