Anti-Paxillin Pxn Antibody (Monoclonal, PXC-10)
Primary Antibody supplied by Boster Bio Read more ›

Product Description
The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | MA1080 |
| Product category | Primary Antibodies, Mouse Monoclonal Antibodies |
| Reactive species | Bovine, Chicken, Hamster, Human, Mouse, Rat |
| Tested applications | IF/ICC, WB |
| Available conjugations | Unconjugated |
| Gene name | PXN |
| Protein name | Paxillin |
| Specificity | No cross reactivity with other proteins. |
| Immunogen | C-terminal part of recombinant chicken paxillin (amino acids 305-559). |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Purification | Ascites |
| Storage | Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles. |
| UniProt | Q66H76 |
| NCBI Gene ID | Human(5829), Mouse(19303), Rat(360820) |
Available variants
| Conjugation | Size |
|---|---|
| Unconjugated | 100 μg/vial |
Key Facts
| Target | Paxillin |
| Also known as | Paxillin;Pxn |
| Concentration | Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml. |
| Species reactivity | Bovine,Chicken,Hamster,Human,Mouse,Rat |
| Observed band | 65 kDa |
| Purity | No cross reactivity with other proteins. |
| Form / buffer | Lyophilized |
| Shelf life | Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles. |
| Host species | Mouse |
| Clonality | Monoclonal |
| Clone number | Clone: PXC-10 |
| Isotype | Mouse IgG1 |
| Conjugation | Unconjugated |
| Non-cross-reactive with | No cross-reactivity with other proteins |
| Tested applications |
IF/ICCWB |
| Dilution range | Immunocytochemistry , 1μg/ml, Human, mouse, rat, chicken, - Western blot, 1-2μg/ml, Human, mouse, rat, chicken |
| Immunogen | C-terminal part of recombinant chicken paxillin (amino acids 305-559). |
| Purification | Ascites |
Reactivity & Application Validation
6 speciess| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | FLOW CYTOMETRY | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Bovine | ||||||||
| Chicken | ||||||||
| Hamster | ||||||||
| Human | ||||||||
| Mouse | ||||||||
| Rat |
Specifications
Western blot, 1-2μg/ml, Human, mouse, rat, chicken
Storage & Stability
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Compliance & Certifications
Not intended for diagnostic or therapeutic use.