Anti-LDL Receptor/LDLR Antibody Picoband®

Boster Bio Anti-LDL Receptor/LDLR Antibody Picoband® catalog # A00076-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

In humans, the LDL receptor protein is encoded by the LDLR gene on chromosome 19. It is mapped to 19p13.2. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	A00076-2
Product category	Primary Antibodies
Reactive species	Human, Rat
Tested applications	ELISA, Flow Cytometry, IHC, IHC-P, WB
Available conjugations	Unconjugated, Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, Fluoro647
Gene name	LDLR
Protein name	Low-density lipoprotein receptor
Specificity	No cross reactivity with other proteins.
Immunogen	E.coli-derived human LDL Receptor/LDLR recombinant protein (Position: Q35-D843).
Host	Rabbit
Clonality	Polyclonal
Isotype	Rabbit IgG
Purification	Immunogen affinity purified.
Storage	Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
UniProt	P01130
NCBI Gene ID	3949

Available variants

Conjugation	Size
Unconjugated	100 μg/vial
Biotin	100 μg/vial
Cy3	100 μg/vial
Fluoro488	100 μg/vial
Fluoro550	100 μg/vial
Fluoro594	100 μg/vial
FITC	100 μg/vial
HRP	100 μg/vial
APC	100 μg/vial
PE	100 μg/vial
Fluoro647	100 μg/vial