Anti-CLDN14 Antibody Picoband®
Primary Antibody supplied by Boster Bio Read more ›

Product Description
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | A06550-1 |
| Product category | Primary Antibodies |
| Reactive species | Human |
| Tested applications | WB |
| Available conjugations | 80 |
| Gene name | CLDN14 |
| Protein name | Claudin-14 |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human CLDN14. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Purification | Immunogen affinity purified. |
| Storage | At -20˚C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freezing and thawing. |
| NCBI Gene ID | 23562 |
Available variants
| Conjugation | Size |
|---|---|
| 80 | 100 μg/vial |
Key Facts
| Target | Claudin-14 |
| Also known as | CLDN14; UNQ777/PRO1571; Claudin-14 |
| Concentration | Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
| Species reactivity | Human |
| Observed band | 24 kDa |
| Form / buffer | Lyophilized |
| Shelf life | At -20˚C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freezing and thawing. |
| Host species | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Conjugation | 80 |
| Tested applications |
WB |
| Dilution range | Western blot, 0.25-0.5 μg/ml, Human |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human CLDN14. |
| Purification | Immunogen affinity purified. |
Reactivity & Application Validation
1 species| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | FLOW CYTOMETRY | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.