Recombinant Mouse BMPRIA/ALK-3 Protein (His Tag)
Recombinant Mouse BMPRIA/ALK-3 Protein (His Tag) supplied by Elabscience with collaborator-provided technical specifications. Read more ›
["Measured by its ability to inhibit recombinant human BMP4 induced activity in MC3T3-E1 Mouse osteoblastic cells. The ED50 for this effect is typically 0.5-2 μg/ml in the presence of 50 ng/ml of recombinant human BMP4. ,"]Product Description
BMPRIA/ALK-3 is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.
Protein profile: reactive species/source: Mouse; expression system: HEK293 Cells; physical form: Lyophilized from sterile PBS, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Mouse ,BMPRIA/ALK-3 ,Recombinant Proteins; predicted molecular weight: 15.8 kDa.
Quality and formulation: purity: > 97 % as determined by reducing SDS-PAGE.; endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method..
Functional evidence: activity: Measured by its ability to inhibit recombinant human BMP4 induced activity in MC3T3-E1 Mouse osteoblastic cells. The ED<sub>50</sub> for this effect is typically 0.5-2 μg/ml in the presence of 50 ng/ml of recombinant human BMP4.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.
Sequence coverage: 15.8 kDa.
Database references: UniProt: NP_033888.2 | NCBI Gene: 12166 | Gene symbol: BMPRIA/ALK-3.
Research Use Only.
Key Facts
| Target | BMPRIA/ALK-3 |
| Also known as | ALK-3, Activin receptor-like kinase 3, Acvrlk3, BMP type-1A receptor, BMP-2/BMP-4 receptor, BMPR-1A, BMPR-IA, Bmpr, Bone morphogenetic protein receptor type-1A, CD292, SKR5, Serine/threonine-protein kinase receptor R5 |
| Species reactivity | Mouse |
| Purity | > 97 % as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Shelf life | 12 months |
| BIOACTIVITY | BINDING | CELL-BASED | IN VIVO | ELISA CAPTURE | |
|---|---|---|---|---|---|
| Mouse |
Specifications
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Manufactured under ISO 14001:2015 quality management standards.
Manufactured under ISO 45001:2018 quality management standards.
Not intended for diagnostic or therapeutic use.
Substance does not appear on the SVHC candidate list.