Manufactured by:ELK Biotechnology
RUO

GABAA Rα6 rabbit pAb

GABAA Rα6 rabbit pAb from ELK Biotechnology

SKU:
ABM107076
Product type
Primary Antibody
TargetGABAA Rα6
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse, Rat
Expression systemCerebellum,
PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

GABAA Rα6 rabbit pAb is a research-use antibody from ELK Biotechnology for studying GABAA Rα6 in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008],

Additional antibody information

Specificity GABAA Rα6 Polyclonal Antibody detects endogenous levels of GABAA Rα6 protein.
Validation evidence captions Western Blot analysis of various cells using GABAA Rα6 Polyclonal Antibody diluted at 1:500 | Western Blot analysis of MOUSE-BRAIN cells using GABAA Rα6 Polyclonal Antibody diluted at 1:500 | Western blot analysis of lysates from HeLa and Jurkat cells, using GABRA6 Antibody. The lane on the right is blocked with the synthesized peptide.
Key facts & specifications
Research areas
>>Neuroactive ligand-receptor interaction, >>Retrograde endocannabinoid signaling, >>GABAergic synapse, >>Taste transduction, >>Morphine addiction, >>Nicotine addiction
Also known as
GABRA6; Gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor subunit alpha-6
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human GABRA6. AA range:61-110
Observed band
51kD
Cellular localization
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Assay type
Antibody validation/application
Source organism
Rabbit
Concentration
1 mg/ml
Working concentration
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Sequence fragment
AA range: 61-110
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Mouse
Rat
Identifiers & database references
Supplier SKU / catalogue number
ES2388
UniProt entry
Q16445
Storage, stability & shipping
Storage conditions
'-20°C/1 year
Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ELK Biotechnology
£220.00