Manufactured by:Elabscience
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Anti-Human/Rat BRCA1 Antibody

Anti-Human/Rat BRCA1 Antibody with collaborator-tested evidence for WB, IHC-P, IF/ICC.

SKU:
ABM7551-1
Product type
Primary Antibodies
TargetBRCA1
ApplicationsWB, IHC-P, IF/ICC
Species / reactivityHuman, Rat

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Anti-Human/Rat BRCA1 Antibody is a research-use antibody from Elabscience for studying BRCA1 in WB, IHC-P, IF/ICC workflows with listed reactivity for Human, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Key facts & specifications
Research areas
Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Also known as
BRCA 1, BRCA1, BRCA1 DNA repair associated, BRCA1/BRCA2 containing complex subunit 1, BRCA1/BRCA2-containing complex, BRCAI, BRCC 1, BRCC1, Breast Cancer 1, Breast Cancer 1 Early Onset, Breast and ovarian cancer susceptibility protein 1, Breast cance, subunit 1
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000
Immunogen
Synthesized peptide derived from human BRCA1 around the non-phosphorylation site of Ser1423.
Molecular weight
208 kDa
Concentration
1 mg/mL
Purification
Affinity purification
Technical note
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHC-PIHC-FrIF/ICCFlow CytIPChIP
Human
Rat
Identifiers & database references
Supplier SKU / catalogue number
E-AB-30669_120μL
Gene ID
672
UniProt accession
P38398
Storage, stability & shipping
Shelf life
12 months from shipping dates
Shipped at
Wet ice (2-8 degrees C)
Short-term storage
2-8 degrees C for up to 1 month
Long-term storage
4 degrees C for up to 12 months. Do not freeze.
Storage buffer
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Aliquoting guidance
Do not freeze. Aliquot only if necessary to avoid repeated opening.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

BRCA1BRCA1 DNA repair associated

View target guide

BRCA1 (BRCA1 DNA repair associated; breast cancer type 1 susceptibility protein) is a nuclear genome-maintenance protein and E3 ubiquitin ligase central to DNA-damage responses, double-strand-break repair and genomic stability.

Biological function: BRCA1 forms a functional heterodimer with BARD1 that has E3 ubiquitin-protein ligase activity. The complex participates in cellular responses to DNA damage and helps coordinate DNA double-strand-break repair, homologous recombination, ubiquitin signalling and maintenance of genome integrity.

Organism
Homo sapiens (Human)
NCBI Gene
672
UniProtKB
P38398
Elabscience
£179.00£143.20