Manufactured by:Elabscience
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Anti-Human/Mouse/Rat Bad Antibody [B746]

Anti-Human/Mouse/Rat Bad Antibody [B746] with collaborator-tested evidence for WB, IHC, IF/ICC, IP, ELISA.

SKU:
ABM1705-1
Product type
Primary Antibodies
TargetBad
ApplicationsWB, IHC, IF/ICC, IP, ELISA
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Anti-Human/Mouse/Rat Bad Antibody [B746] is a research-use antibody from Elabscience for studying Bad in WB, IHC, IF/ICC, IP, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Key facts & specifications
Research areas
Cell Biology, Cancer, Metabolism
Also known as
BCL2L, BBC, BAD, BBC2, BCL2L8, BBC6, AI325008, BBC 2, Bcl 2 Antagonist of Cell Death, Bcl 2 Binding Component 6, BCL X / BCL 2 Binding Protein, BCL X Binding Protein, Bcl XL/Bcl 2 Associated Death Promoter, Bcl2 antagonist of cell death, BCL2 antagonist of cell death protein, BCL2 associated agonist of cell death, Bcl2 Associated Death Promoter, BCL2 binding component 6, BCL2 binding protein, Bcl2 Like 8 Protein, Bcl-2-binding component 6, Bcl2-L-8, Bcl-2-like protein 8, Bcl-XL/Bcl-2-associated death promoter, Proapoptotic BH3 Only Protein
Host species
Rabbit
Clonality
Monoclonal
Clone number
B746
Isotype
IgG,κ
Dilution range
IHC 1:200-1:1000, WB 1:1000-1:5000, IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200,
Immunogen
Recombinant Human Bad protein
Observed band
23 kDa
Molecular weight
18 kDa
Concentration
0.2 mg/mL
Purification
Protein A
Technical note
IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHC-PIHC-FrIF/ICCFlow CytIPChIPIHCELISA
Human
Mouse
Rat
Identifiers & database references
Supplier SKU / catalogue number
AN300995L_100μL
UniProt accession
Q92934
Storage, stability & shipping
Shelf life
12 months from shipping dates
Shipped at
Wet ice (2-8 degrees C)
Short-term storage
2-8 degrees C for up to 1 month
Long-term storage
4 degrees C for up to 12 months. Do not freeze.
Storage buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Aliquoting guidance
Do not freeze. Aliquot only if necessary to avoid repeated opening.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

BADBCL2 associated agonist of cell death

View target guide

BCL2 associated agonist of cell death (BAD) is a pro-apoptotic BH3-only BCL2-family regulator whose activity is strongly controlled by phosphorylation. When active, BAD can engage anti-apoptotic BCL2-family proteins and shift mitochondrial signalling toward intrinsic apoptosis. This page groups ABMIUM catalogue reagents for BAD signalling and cell-death research.

Biological function: BAD is regulated by phosphorylation at multiple serine residues. Survival signalling can promote phosphorylated BAD association with 14-3-3 proteins, limiting its pro-apoptotic activity. Dephosphorylated BAD can bind anti-apoptotic BCL2-family proteins such as BCL-XL and BCL2, favouring activation of the mitochondrial apoptosis programme.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
572
UniProtKB
Q92934
Elabscience
£238.00£190.40