Manufactured by:Elabscience
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Recombinant Human TNF-alpha/TNFA Protein

Recombinant Human TNF-alpha/TNFA Protein supplied by Elabscience with collaborator-provided technical specifications.

SKU:
ABM18063-1
Product type
Cytokines
TargetTNF
Species / reactivityHuman
Purity>95% by SDS-PAGE

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Recombinant Human TNF-alpha/TNFA Protein is a research-use recombinant protein from Elabscience preparation representing TNF-alpha supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Key facts & specifications
Research areas
Signal Transduction, Cardiovascular, Cancer, immunology, metabolism
Also known as
Cachectin, TNF, TNF-Alpha, TNF-a, TNFA, TNFSF2, Tumor Necrosis Factor, Tumor Necrosis Factor Ligand Superfamily Member 2
Modification
None
Molecular weight
17.5 kDa
Form / buffer
Lyophilized
Activity
Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 10-50 pg/ml.
Endotoxin level
< 0.01 EU per μg of the protein as determined by the LAL method.
Sequence
Val77-Leu233
Technical note
Please refer to the printed manual for detailed information.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesBioactivityBindingCell-BasedIn VivoELISA Capture
Human
Identifiers & database references
Supplier SKU / catalogue number
PKSH033490_10ug
Gene symbol
TNF-alpha
Gene ID
7124
UniProt accession
P01375
Storage, stability & shipping
Shelf life
12 months
Shipped at
This product is provided as lyophilized powder which is shipped with ice packs.
Short-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Long-term storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Aliquoting guidance
Reconstitute entire vial immediately. Aliquot working stock; avoid repeated freeze-thaw.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

TNFTumor necrosis factor

View target guide

TNF encodes a multifunctional pro-inflammatory cytokine in the tumour necrosis factor superfamily. This target hub connects accepted names and identifiers with ABMIUM antibodies, ELISA kits and related assay products.

Biological function: TNF is produced as a membrane-associated cytokine and can be released in soluble form. Signalling through TNFRSF1A (TNFR1) and TNFRSF1B (TNFR2) contributes to regulation of inflammation, immune responses, cell survival, differentiation and cell death.

Organism
Homo sapiens (Human)
NCBI Gene
7124
UniProtKB
P01375
Elabscience
£43.00£34.40